Mirra Andreeva was left in tears after Barbora Krejcikova came from behind to knock the 19-year-old Roland Garros champion out of Wimbledon in a gruelling three-set battle on Centre Court.
Naomi Osaka continued her resurgent Wimbledon campaign, defeating Daria Kasatkina 6-3 6-2 to reach the fourth round at the All England Club for the first time in her career.
With a visor embroidered in Tagalog reading "Once it grows, it cannot be stopped," Alexandra Eala battled past Maya Joint to become the first Filipina to reach a Grand Slam third round in the Open Era.
Grigor Dimitrov fought back tears after defeating 15th seed Jakub Mensik 7-6 4-6 7-5 6-3, extending his emotional return to Wimbledon 12 months after a devastating injury ended his campaign against Sinner.
Fresh off his maiden Grand Slam title at Roland Garros, Alexander Zverev cruised past Valentin Royer 6-1 6-3 7-6 and declared a deep run at Wimbledon "definitely possible this year."
Flavio Cobolli gave a hilariously honest post-match interview after completing a marathon two-day victory over Mario Navone at Wimbledon, declaring "I completely hate my life" during the rain-interrupted epic.